A global study has linked exposure to phthalates in plastics and cosmetics to over 368,000 heart-related deaths in 2018 among adults aged 55 to 64.
Phthalates, sometimes called “everywhere chemicals,” are used to make plastics flexible and are found in food containers, shampoo, cosmetics, children’s toys, and even medical tubing.
Researchers from New York University’s Grossman School of Medicine examined the global burden of one of the most common phthalates—Di(2-ethylhexyl)phthalate, or DEHP—and its impact on heart disease mortality.
Lead researchers analyzed data from dozens of population studies across 200 countries and matched urine samples containing breakdown products of DEHP with global death records.
Their findings suggest that DEHP exposure may have contributed to more than 10% of heart-related deaths worldwide in the 55 to 64 age group.
Phthalates have long been linked to a range of health risks. In males, these chemicals can disrupt testosterone, a hormone vital to heart health. Earlier studies also connected phthalates to reproductive issues, including lower sperm counts, genital malformations in baby boys, and undescended testes.
Research has further associated them with cancer, asthma, childhood obesity, and neurodevelopmental delays.
Dr. Leonardo Trasande, a professor of pediatrics and population health at NYU and one of the study’s authors, said phthalates can trigger inflammation in the arteries, increasing the risk of cardiovascular events.
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The study’s co-author, Sara Hyman, emphasized the urgent need to understand and reduce global exposure to these chemicals.
Geographically, Africa accounted for 30% of the cardiovascular deaths tied to DEHP exposure, while East Asia and the Middle East together accounted for another 25%.
The research marks the first global estimate of deaths linked to DEHP, highlighting its significant health and economic impact.
Though the American Chemistry Council declined to respond directly to the findings, consumer health advocates stress the importance of reducing phthalate exposure.
Experts recommend avoiding plastic food containers, especially for heating. Instead, use glass, ceramic, or stainless steel.
Other tips include choosing unscented personal care and cleaning products, buying fresh rather than canned foods, and steering clear of plastics labeled with recycling codes 3, 6, and 7.
Regular handwashing and avoiding air fresheners may also help reduce risk. As concern grows, the findings spotlight a hidden yet widespread threat from everyday chemical exposure.
BBC News














